Burkholderia cepacia and cystic fibrosis: do natural environments present a potential hazard?

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Burkholderia cepacia complex and cystic fibrosis

The bacteriae previously known as ‘Burkholderia cepacia’ have been reclassified as nine closely related species, sometimes referred to as ‘genomovars’ (Table 1), (Coenye et al, 2001; Mahenthiralingam et al, 2002). Collectively these are commonly referred to as ‘Burkholderia cepacia complex’ (Bcc). The various genomovars have different pathogenic potential (Keig et al, 1999; Bevivino et al, 2002...

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Chronic Burkholderia cepacia bronchiectasis in a non-cystic fibrosis individual.

Infection with Burkholderia cepacia due to social contact is well described in patients with cystic fibrosis. However, social transmission to non-cystic fibrosis individuals or chronic colonisation in non-cystic fibrosis individuals has not been described. A report of B cepacia bronchiectasis is presented where a previously healthy mother of two cystic fibrosis children colonised with B cepacia...

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Evidence of transmission of Burkholderia cepacia, Burkholderia multivorans and Burkholderia dolosa among persons with cystic fibrosis.

Previous studies have identified specific Burkholderia cepacia complex strains that are common to multiple persons with cystic fibrosis (CF). Such so-called epidemic strains have an apparent enhanced capacity for inter-patient spread and reside primarily in Burkholderia cenocepacia (formerly B. cepacia complex genomovar III). We sought to identify strains from B. cepacia complex species other t...

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Burkholderia cepacia complex in Indian cystic fibrosis patients

In India, there are no precise reports of the prevalence of Burkholderia cepacia complex (BCC) infections due to the lack of awareness and difficulty in identification by routine clinical laboratories. In most cases, BCC has been ambiguously reported as nonfermentative Gram-negative bacilli (NFGNB) or simply Pseudomonas spp.1,2. For this reason, reports of disease due to BCC are rare and BCC ha...

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Epidemiology of Burkholderia cepacia complex colonisation in cystic fibrosis patients.

In Belgian cystic fibrosis (CF) clinics, sputum samples are evaluated on selective MAST medium routinely every 3 months. In this study, in 1993 and 1999, isolates were further examined by recA restriction fragment length polymorphism analysis and pulsed-field gel electrophoresis of genomic DNA restricted with SpeI. In 1993, 12 patients were colonised with Burkholderia cepacia complex (Bcc): B. ...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 1995

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.33.4.1001-1004.1995